Thyroid Disorders

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Course Credit: 1 hour

This module will focus on the management of thyroid disorders from a pharmacology perspective.

Learning Objectives

  • Describe the role of iodine within the thyroid gland
  • Identify clinical manifestations of decompensated hypo- and hyperthyroidism
  • Discuss pharmacologic interventions for decompensated hypo- and hyperthyroidism
  • Utilize case-based scenarios to design optimal medication regimens for decompensated thyroid disorders

2 thoughts on “Thyroid Disorders”

  1. I was challenged by a biochemist on the issue of hypothyroidism causing hyponatraemia. They stated this simply isn’t true, save for patients in extremis in a myxoedemic coma. Is there good evidence that hypothyroidism causes hyponatraemia. How common is it?
    Or is it just a theoretical concern which we don’t see in clinical practice.?

    1. In short, no there is no good evidence, and hyponatremia likely exists in an association with myxedema.

      It appears that outside of myxedema/decompensated hypothyroid, there is virtually no difference in the incidence of hyponatremia among euthyroid and hypothyroid patients ( But as your colleague stated, there appears to be at least an association in the extreme spectrum of hypothyroidism. Based on a limited evidence, in an infrequent clinical scenario, it is difficult to assign an incidence. The best summary paper I’ve found complies the available limited evidence, minus some case series/reports that are out there. (

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