Vasopressors and Inotropes

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Course Credit: 1 hour

The contents of the traditional “vasopressors and inotropes” pharmacology textbook consist of a brief discussion about mechanisms of action, a bit of pharmacokinetics, some structures sprinkled in for confusion, and a table with +++s or —s denoting receptor affinities. While this information can be useful, it is critical to recognize that the literature feeding these texts is largely based on animal models, often with open chest physiology and may not reflect patients with shock in the emergency department, ICU, or anywhere else.

Similarly, understanding the physiologic effects of these drugs to reach a resuscitationist’s knowledge level requires an exceptional foundational knowledge base upon which to build pharmacotherapeutic understanding. Please review these:

AuthorCraig Cocchio, PharmD, BCPS
Emergency Medicine Pharmacist, Trinity Mother Frances Hospital
AuthorDouglas Gowen, PharmD, BCPS
Emergency Medicine Pharmacist, Glens Falls Hospital (Glens Falls, New York)
ReviewerJill Logan, PharmD, BCPS
Emergency Medicine Pharmacist, University of Maryland Medical Center
ReviewerDavid Juurlink, BPharm, MD, PhD, FRCPC
Professor of Medicine, University of Toronto
Lead EditorBryan Hayes, PharmD, FAACT
Emergency Medicine Pharmacist, Clinical Associate Professor; University of Maryland

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